Minimally Invasive Technology for Obstructive Sleep Apnea




People with untreated sleep apnea face more than 3x the risk of premature death and more than 5xthe risk of cardiovascular mortality.



of all patients diagnosed with sleep apnea and prescribed CPAP therapy will abandon treatment or fail on CPAP.

Significant Economic Cost

$65 – $165B

Estimated total annual economic costof moderate to severe OSA in the U.S. This is greater than asthma, heart failure, stroke and hypertensive disease ($20-$80B).

Young, T., Finn, L., Peppard, P.E., et al. Sleep Disordered Breathing and Mortality: Eighteen-Year Follow-up of the Wisconsin Sleep Cohort. Sleep. Sleep Research Society. 2008 Aug 1; 31(8): 1071-1078 American Sleep Apnea Association. CPAP Therapy, Attitude, and Expectations. Can Respir J. Long-term compliance with continuous positive airway pressure in patients with obstructive sleep apnea. Canadian Respiratory Journal 2008 Oct; 15(7): 365–369. Harvard Medical School Division of Sleep Medicine, The price of fatigue; The surprising economic costs of unmanaged sleep apnea, December 2010 Sutherland K, Phillips CL, Cistulli PA, Efficacy versus effectiveness in the treatment of obstructive sleep apnea. CPAP and oral appliances. Journal of Dental Sleep Medicine 2015, 2(4) 175-181

Prevalence of Comorbidities: Top 5 Conditions
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Pinto, J.A., Riberio, D. K., da Silva Cavallini, A. F., et al. Comorbidities Associated with Obstructive Sleep Apnea: a Retrospective Study. International Archives Otorhinolaryngol. 2016 Apr; 20(2): 145–150.


XII Medical is comprised of a team of some of the best minds in the medical industry. Our team represents a wide range of knowledge across disciplines crucial to a successful venture in today’s ever-changing market. We are focused on developing an innovative device to help people with moderate to severe sleep apnea sleep better.

Minimally Invasive

Our next-generation technology is patient-centered to proactively treat obstructive sleep apnea.

Rooted in Science

Focused on the development of therapy derived from research into the origins of obstructive sleep apnea.

Clinical Expertise

Our technology leverages clinical research and technical expertise of the Cleveland Clinic.

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